## Summary of "A Simple Instrument Could Find Martian DNA - If It Exists" **News Title:** A Simple Instrument Could Find Martian DNA - If It Exists **Source:** Universe Today **Author:** Andy Tomaswick **Published:** August 14, 2025 This article discusses the ongoing race among astrobiologists to detect evidence of extant life on Mars before potential human colonization contaminates the planet. A new paper by Christopher Temby and Jan Spacek of the Agnostic Life Finder (ALF) team proposes a method to definitively prove the existence of Martian life by finding polyelectrolyte polymers, such as DNA. ### Key Findings and Conclusions: * **The Search for Martian Life:** Astrobiologists are urgently trying to determine if life exists on Mars before human colonization efforts inadvertently introduce Earth's biosphere, potentially obscuring or destroying any native Martian life. * **Polyelectrolytes as Biosignatures:** The ALF team's research focuses on polyelectrolyte polymers, like DNA and RNA, as crucial biosignatures. These molecules are vital for conveying information between generations and are likely to be present in any form of life, even if it evolved separately from Earth's. * **The "Ladder of Life Detection":** A 2018 NASA paper, known as the "Ladder of Life Detection," identified polyelectrolytes as potential biosignatures but also highlighted challenges in their detection. * **ALF Instrument's Solution to Detection Challenges:** * **Dilution Problem:** Polyelectrolytes can be highly dilute, falling below detection thresholds. The ALF system addresses this by using **electrodialysis** and a series of **nano-pore based filters**. This process concentrates the charged polyelectrolytes by separating them from smaller salt ions (like potassium and magnesium) using an electric field and specialized filters. * **Survivability Issue:** The "Ladder of Life Detection" paper noted that polyelectrolytes have limited survivability in liquid water due to hydrolysis. The ALF team, however, views this as a strength. They argue that if polyelectrolytes are unequivocally detected, it strongly suggests the presence of *extant* life actively creating them, as older samples would have degraded. ### Important Recommendations and Future Outlook: * **Focus on High-Confidence Biosignatures:** The research emphasizes the importance of seeking high-confidence biosignatures, such as polyelectrolytes, in Martian ice. * **Potential for Discovery:** If the ALF system receives continued support, it could provide scientists with data on Martian DNA or its equivalent, potentially before the planet is significantly altered by human activity. ### Notable Risks and Concerns: * **Contamination:** The primary concern is the potential contamination of Mars with Earth's biosphere due to ongoing colonization efforts, which could make it impossible to identify native Martian life. * **Funding Uncertainty:** The future of the ALF system is uncertain due to potential budget cuts from NASA, which initially funded its development through a NIAC grant. The continuation of this funding is critical for the instrument's progress. This news highlights a critical scientific endeavor to understand the potential for life on Mars, with a promising technological approach being developed by the ALF team. The success of this mission hinges on overcoming technical challenges and securing continued financial support.
A Simple Instrument Could Find Martian DNA - If It Exists
Read original at Universe Today →Mars still holds the promise of being one of the first places in the solar system humanity will colonize. However, if there was evolutionarily distinct, extant life on the planet, it might sway the heart of even the most ardent Mars colonization fans. So astrobiologists are in a race against time to try to determine whether or not such life exists, before the entire planet becomes an analogue of the Earth’s biosphere, if only unintentionally, and only a shadow of the ones that exists here.
A new paper from the Christopher Temby and Jan Spacek of the Agnostic Life Finder (ALF) team discusses one of the most promising ways to prove definitively that life exists on the Red Planet - finding polyelectrolyte polymers - in other words, DNA.DNA isn’t the only type of polyelectrolyte polymer in our own biosphere - RNA is another example.
But the reason that finding a polyelectrolyte is so important is because of their ability to convey information between generations. Mars could have an entirely separate way of passing down genetic information from anything we know of on Earth, but it would still likely look at least something like a polyelectrolyte polymer.
In a landmark paper in 2018, NASA staff laid out what is now known as the “Ladder of Life Detection”, where polyelectrolytes are discussed as a possible biosignature. However, there are also a few weaknesses the molecules exhibit that have to be overcome by any instrument planning to find them.ALF Presentation of its device at a NIAC conference.
Credit - ALFA Mars YouTube ChannelThe first problem is that the polyelectrolytes could be so dilute that they wouldn’t reach the detection threshold of the instrument designed to find them, especially if the total amount of biomass is miniscule compared to that found on Earth. This problem is easily solved by concentrating the polyelectrodes using electrodialysis and a set of porous membranes.
In this system, first the sample is combined with water, and then that water is subjected to an electric field. Since polyelectrolytes are charged particles, they move in an electric field, as do natural salts such as potassium and magnesium (which is what typical dialysis is attempting to do for patients on Earth).
However, polyelectrolytes are physically much larger than the salt ions, so the ALF system has a series of nano-pore based filters that would allow the salts to keep moving farther, while holding the polyelectrolytes in a specific chamber. Subjecting a sample to the electric field for long enough would migrate all of the polyelectrolytes to one specific area on one side of the nanofilter, and allow a much high concentration that should be able to pass the detection threshold of the instrument, if enough of the molecules are actually in the sample.
The second problem mentioned by the Ladder of Life Detection paper is actually a strength according to the ALF researchers. Polyelectrodes don’t survive long when subjected to water - in the paper’s language “its survivability in liquid water is limited by hydrolysis”. Rather than seeing that as a problem that must be overcome, the ALF team thinks that simply means that if polyelectrodes are unequivocally detected there must be some extant life creating them, since older samples from life long ago would have been destroyed by the time the sampler came along.
Fraser tells the story of the search for life on Mars.As humanity continues to move towards Mars colonization, the window for finding and analyzing unique Martian life is continuing to close. We previously discussed how exactly the ALF would be implemented, and this sub-section of the instrument seems promising in finding this one particular sign of life.
But as with the instrument as a whole, it’s unclear whether budget cuts from NASA, which funded the original development of the ALF through a NIAC grant, will allow continuing support of the system or not. If it does, data on Martian DNA, or its equivalent, may someday be at scientists’ fingertips - hopefully before it's contaminated by any from Earth.
Learn More:C. Temby & J. Spacek - 21st-Century Astrobiology Missions Should Seek These High-Confidence Biosignatures in Mid-Latitude Martian IceM. Neveu et al. - The Ladder of Life DetectionUT - Mars Life Explorer Should Include An Agnostic Life FinderUT - Searching for Life on Mars in the Snow and Ice
